USA Research Featured In National Journal

USA Health Mitchell Cancer Institute scientists have extensively researched nicotinamide adenine dinucleotide (NAD+) and the role it plays in cancer research and treatment effectiveness for patients. Highlighted in the October 2020 special issue of scientific journal DNA Repair, the article, “NAD+ Mediated Regulation of Mammalian Base Excision Repair,” describes several cell pathways influenced by NAD+ that can cause cells to become damaged or mutate. MCI researchers are using their findings to better understand why some cancer treatment responses may be affected differently depending on the patient’s vitamin B3 dietary intake and how a cancerous tumor can grow and spread because of a patient’s metabolism. The work conducted at the Mitchell Cancer Institute was chosen along with 23 research labs from around the world to contribute short review articles.